Helps relieve joint pain associated with osteoarthritis. It has been used as an anti-inflammatory and analgesic.The Commission E approved the use of devil’s claw root for degenerative disorders of the locomotor system. Devil’s claw root has been used to treat painful arthroses, tendonitis, rheumatism and arthritis.The constituents most likely responsible for devil’s claw root’s anti-inflammatory effects are its iridoids, particularly harpagoside.